Invention Grant
- Patent Title: Hematopoietic stem cell identification and isolation
- Patent Title (中): 造血干细胞鉴定和分离
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Application No.: US12389143Application Date: 2009-02-19
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Publication No.: US07919316B2Publication Date: 2011-04-05
- Inventor: Omer H. Yilmaz , Mark J. Kiel , Sean Morrison , Toshihide Iwashita
- Applicant: Omer H. Yilmaz , Mark J. Kiel , Sean Morrison , Toshihide Iwashita
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Casimir Jones, S.C.
- Main IPC: C12N5/0789
- IPC: C12N5/0789 ; C12N5/074
Abstract:
The present invention relates to methods of identifying, collecting and isolating hematopoietic stem cells (HSCs) and compositions of purified HSCs. Specifically, the present invention provides methods of isolating and purifying CD150+ HSCs, CD48− HSCs, and CD244− HSCs. The present invention also relates to purified cell samples with enriched CD150+ HSCs, CD48− HSCs, and CD244− HSCs populations, as well as methods of treating subjects with such compositions.
Public/Granted literature
- US20090227019A1 HEMATOPOIETIC STEM CELL IDENTIFICATION AND ISOLATION Public/Granted day:2009-09-10
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