Invention Grant
- Patent Title: Method of improving sensor detection of target molcules in a sample within a fluidic system
- Patent Title (中): 改进流体系统中样品中靶标的传感器检测方法
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Application No.: US11917655Application Date: 2006-06-15
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Publication No.: US07919330B2Publication Date: 2011-04-05
- Inventor: Peter Patrick de Guzman , Wayne Po-Wen Liu , Uichong Brandon Yi , Chang-Jin Kim
- Applicant: Peter Patrick de Guzman , Wayne Po-Wen Liu , Uichong Brandon Yi , Chang-Jin Kim
- Applicant Address: US NC Research Triangle Park
- Assignee: Advanced Liquid Logic, Inc.
- Current Assignee: Advanced Liquid Logic, Inc.
- Current Assignee Address: US NC Research Triangle Park
- Agency: Ward and Smith, P.A.
- Agent William A. Barrett
- International Application: PCT/US2006/023459 WO 20060615
- International Announcement: WO2006/138543 WO 20061228
- Main IPC: G01N33/558
- IPC: G01N33/558

Abstract:
Methods of improving microfluidic assays are disclosed. Assays can be improved (better signal to noise ratio) by using sessile drop evaporation as an analyte concentration step (enhanced signal) and repeated passes of wash droplets as a means to reduce non-specific binding (noise reduction). In addition multiple massively parallel analyses improve the statistical precision of the analyses.
Public/Granted literature
- US20090042319A1 Biosensor Detection By Means Of Droplet Driving, Agitation, and Evaporation Public/Granted day:2009-02-12
Information query
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