Invention Grant
- Patent Title: Method of inhibiting prostate cancer cell proliferation
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Application No.: US10517256Application Date: 2003-06-10
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Publication No.: US07919458B2Publication Date: 2011-04-05
- Inventor: Garry George Graham , Qihan Dong
- Applicant: Garry George Graham , Qihan Dong
- Applicant Address: AU New South Wales
- Assignee: Scott, Kieran, Francis
- Current Assignee: Scott, Kieran, Francis
- Current Assignee Address: AU New South Wales
- Agency: Nixon & Vanderhye
- Priority: AUPS2826 20020607
- International Application: PCT/AU03/00719 WO 20030610
- International Announcement: WO2004/064822 WO 20040805
- Main IPC: A61K38/12
- IPC: A61K38/12

Abstract:
The present invention relates to a method of inhibiting or reducing the proliferation of prostate cancer cells, such as androgen independent prostate cancer (AIPC) cells, the method comprising administering to the cells a PLA2 inhibitor. In one embodiment the PLA2 inhibitor is a conformationally constrained molecule derived from a peptide consisting essentially of amino acid residues 70-74 of a human sPLA2-IIA protein, or the equivalent residues in other sPLA2 proteins.
Public/Granted literature
- US20080113343A1 Method of Inhibiting Prostate Cancer Cell Proliferation Public/Granted day:2008-05-15
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