Invention Grant
US07919490B2 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
有权
6-取代的2-（苯并咪唑基）嘌呤和嘌呤酮衍生物用于免疫抑制
- Patent Title: 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
- Patent Title (中): 6-取代的2-（苯并咪唑基）嘌呤和嘌呤酮衍生物用于免疫抑制
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Application No.: US11867562Application Date: 2007-10-04
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Publication No.: US07919490B2Publication Date: 2011-04-05
- Inventor: Irina Neagu , David Diller , Celia Kingsbury , Adolph C. Bohnstedt , Michael J. Ohlmeyer , Vidyadhar Paradkar , Nasrin Ansari
- Applicant: Irina Neagu , David Diller , Celia Kingsbury , Adolph C. Bohnstedt , Michael J. Ohlmeyer , Vidyadhar Paradkar , Nasrin Ansari
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Agent Ram W. Sabnis
- Main IPC: C07D473/32
- IPC: C07D473/32 ; C07D473/18 ; A61K31/52 ; A61K31/522 ; A61P37/06 ; A61P11/06 ; A61P35/02 ; C07D239/48 ; C07D239/50 ; C07D405/12 ; C07D405/14
Abstract:
The present invention provides novel purinones and purines useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection. The compounds are of the general formulae I and II shown below, in which Q is selected from the group consisting of CX and nitrogen; and A is chosen from the group consisting of H, (C1-C6) alkyl, heteroaryl, and aryl:
Public/Granted literature
- US20080214580A1 6-SUBSTITUTED 2-(BENZIMIDAZOLYL)PURINE AND PURINONE DERIVATIVES FOR IMMUNOSUPPRESSION Public/Granted day:2008-09-04
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