Invention Grant
- Patent Title: 3-phenylpropionic acid derivatives
- Patent Title (中): 3-苯基丙酸衍生物
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Application No.: US11740820Application Date: 2007-04-26
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Publication No.: US07919515B2Publication Date: 2011-04-05
- Inventor: Zbigniew Majka , Katarzyna Ewa Rusin , Andrzej Wojciech Sawicki , Krzysztof Kurowski , Katarzyna Joanna Matusiewicz , Tomasz Stawinski , Daniel Sulikowski
- Applicant: Zbigniew Majka , Katarzyna Ewa Rusin , Andrzej Wojciech Sawicki , Krzysztof Kurowski , Katarzyna Joanna Matusiewicz , Tomasz Stawinski , Daniel Sulikowski
- Applicant Address: PL Czosnow K/Warsawy
- Assignee: Adamed Sp. z o.o.
- Current Assignee: Adamed Sp. z o.o.
- Current Assignee Address: PL Czosnow K/Warsawy
- Agency: Fish & Richardson P.C.
- Priority: PL371841 20041220
- Main IPC: A61K31/423
- IPC: A61K31/423

Abstract:
The invention relates to new compounds, being 3-phenylpropionic acid derivatives of formula I wherein W represents COOH group or its bioisosters, or —COO—C1-C4-alkyl group; Y represents NH, N—C1-C10-alkyl, O, or S; Z represents NH, N—C1-C10-alkyl, N-aryl, N-heteroaryl, S, or O; X represents O, S, NH, N—C1-C10-alkyl, N-aryl, NSO2—C1-C10-alkyl, N—SO2-aryl, or N—SO2-heteroaryl; R, to R8 each independently represent hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive; and pharmaceutically acceptable salts thereof. The compounds are the ligands of PPAR-gamma receptor and are useful as medicaments.
Public/Granted literature
- US20070219259A1 NEW 3-PHENYLPROPIONIC ACID DERIVATIVES Public/Granted day:2007-09-20
Information query
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