Invention Grant
- Patent Title: Methods and compositions for inhibition of BCL6 repression
- Patent Title (中): 用于抑制BCL6抑制的方法和组合物
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Application No.: US10582662Application Date: 2004-12-16
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Publication No.: US07919578B2Publication Date: 2011-04-05
- Inventor: Ari M. Melnick , Jonathan D. Licht , Gilbert Privé , Khaja Farid Ahmad
- Applicant: Ari M. Melnick , Jonathan D. Licht , Gilbert Privé , Khaja Farid Ahmad
- Agency: Amster, Rothstein & Ebenstein LLP
- International Application: PCT/US2004/042418 WO 20041216
- International Announcement: WO2005/058939 WO 20050630
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K51/00

Abstract:
Provided are peptides or mimetics that block corepressor binding to a BCL6 lateral groove. Also provided are methods of blocking corepressor binding to the BCL6 lateral groove. Additionally, methods of inhibiting BCL6 repression in a mammalian, cell, and methods of treating a mammal with cancer are provided.
Public/Granted literature
- US20090018083A1 Methods and compositions for inhibition of bcl6 repression Public/Granted day:2009-01-15
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