Invention Grant
US07919625B2 4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (CML)
有权
用于治疗慢性骨髓性白血病（CML）的4-苯胺基-3-喹啉甲腈
- Patent Title: 4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (CML)
- Patent Title (中): 用于治疗慢性骨髓性白血病（CML）的4-苯胺基-3-喹啉甲腈
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Application No.: US12139834Application Date: 2008-06-16
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Publication No.: US07919625B2Publication Date: 2011-04-05
- Inventor: Frank Boschelli , Jennifer M. Golas , Kim T. Arndt
- Applicant: Frank Boschelli , Jennifer M. Golas , Kim T. Arndt
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Agent David Rubin; Jeffrey H. Tidwell
- Main IPC: C07D215/38
- IPC: C07D215/38
Abstract:
Compounds of the formula: wherein: n is an integer from 1-3; X is N, CH, provided that when X is N, n is 2 or 3; R is alkyl of 1 to 3 carbon atoms; R1 is 2,4-diCl, 5-OMe; 2,4-diCl; 3,4,5-tri-OMe; 2-Cl, 5-OMe; 2-Me, 5-OMe; 2,4-di-Me; 2,4-diMe-5-OMe, 2,4-diCl, 5-OEt; R2 is alkyl of 1 to 2 carbon atoms, and pharmaceutically acceptable salts thereof.
Public/Granted literature
- US20100029677A1 4-ANILINO-3-QUINOLINECARBONITRILES FOR THE TREATMENT OF CHRONIC MYELOGENOUS LEUKEMIA (CML) Public/Granted day:2010-02-04
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