An apparatus and method for data transmission and an apparatus and method for driving an image display device using the same are disclosed, in which transition of data is minimized during data transmission to minimize electromagnetic interference. The apparatus for data transmission includes a data modulator modulating low bits excluding the most significant bit (MSB) in response to the MSB of input data, and a data restorer restoring the modulated data transmitted from the data modulator to their original data in response to the MSB. Since the low data bit excluding the MSB data are inverted in response to the MSB data of the input data, the number of times of data transition can be reduced to reach half, thereby minimizing electromagnetic interference.