The automatic calibration of a sensor panel is disclosed by varying the amplitude of an input stimulus Vstim to simulate a full-touch condition and calibrating each pixel of the sensor panel in accordance with the difference between the simulated full-touch condition and a baseline full-touch condition. To accomplish this, a baseline full scale output FS_targ_cal can be measured at during pre-delivery calibration for each pixel using a test fixture capable of applying a no-touch to full-touch condition given a nominal Vstim. A full-touch condition can then be emulated for each pixel by lowering Vstim until the current full scale output FS_targ_current equals FS_targ_cal, and determining the Vstim value Vstim_cal at that point. During field calibration, Vstim_cal can be applied to each pixel to simulate a full-touch condition, and FS_targ_current can be obtained and compared against FS_targ_cal. Each analog channel can then be tuned so that in subsequent full-touch conditions, FS_targ_current will approximately equal FS_targ_cal.