A system and a method is disclosed for universal operation of an internal-combustion engine (2), comprising at least an actuator connected to a working device of the engine, an electronic card (3) including a recording medium for a programmable logic FPGA component and a card synchronization component (9, 10) for synchronizing the card according to the engine cycle. The method, generates, in the component, an angular reference point in the engine cycle for each cylinder; generates, through the component, actuator control pulses, the pulses being parameterizable in phase and in duration, independent and linked with a single cylinder, performing multiplexing of the pulses to distribute the pulses over at least one of the physical outputs of the card specific to the cylinder considered; and controlling at least one of the actuators linked with one of the physical outputs of the card specific to the cylinder considered, with at least one of the control pulses.