The invention is generally directed to systems and methods for medical care, and more particularly to systems and methods for voice control of a medical device. A first embodiment includes a voice controlled surgical system, such as a phacoemulsification system, a microphone coupled to the surgical system, and a voice controlled computer interface coupled with the surgical system. The voice controlled interface is configured to receive a request to invoke a voice command via the microphone, to listen for a voice command upon receipt of a valid request to invoke a voice command, and to forward a valid voice command upon receipt of the valid voice command to the surgical system for execution.