A barb clamp for use with a flexible tube is taught, the flexible tube having an inner bore defined by a predetermined inner diameter for providing a fluid flow path. The barb clamp includes a barb connector having the same predetermined inner diameter as the flexible tube and a tapered end insertable into the tube. A sleeve and collet lock over the tubing and barb connector to prevent liquid material entering between the barb and tube. The tapered end of the barb connector terminates at a point so that there is no transition between the inner diameter of the tube and the inner diameter of the barb connector to provide no pressure differential in the tube between the outside and inside of the barb clamp.