Invention Grant
- Patent Title: Method of determining a cellular response to a biological agent
- Patent Title (中): 确定对生物制剂的细胞反应的方法
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Application No.: US11283481Application Date: 2005-11-18
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Publication No.: US07923206B2Publication Date: 2011-04-12
- Inventor: Barbara Robertson , Devin Leake , Kathryn Robinson , William S. Marshall , Anastasia Khvorova
- Applicant: Barbara Robertson , Devin Leake , Kathryn Robinson , William S. Marshall , Anastasia Khvorova
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Workman Nydegger
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/02 ; C07H21/04
Abstract:
A method of determining a cellular response to a biological agent can be preformed in the presence of gene silencing. Such a method can include the use of siRNA in order to silence various genes in the cell in order to monitor the cellular response to the biological agent when a gene has been silenced. Accordingly, the response of a cell having a silenced gene to a biological agent can be indicative of which genes may be responsible for normal or abnormal cellular responses to various synthetic and natural biological agents such as active agents or pathogens.
Public/Granted literature
- US20060110766A1 Method of determining a cellular response to a biological agent Public/Granted day:2006-05-25
Information query
