Invention Grant
- Patent Title: Methods and compounds for controlled release of recombinant parvovirus vectors
- Patent Title (中): 控释重组细小病毒载体的方法和化合物
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Application No.: US11697194Application Date: 2007-04-05
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Publication No.: US07923436B2Publication Date: 2011-04-12
- Inventor: Paul E. Monahan , Richard Jude Samulski , Joseph E. Rabinowitz
- Applicant: Paul E. Monahan , Richard Jude Samulski , Joseph E. Rabinowitz
- Applicant Address: US NC Chapel Hill
- Assignee: University of North Carolina - Chapel Hill
- Current Assignee: University of North Carolina - Chapel Hill
- Current Assignee Address: US NC Chapel Hill
- Agency: Myers Bigel Sibley & Sajovec, P.A.
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61K39/23
Abstract:
The invention uses recombinant parvoviruses, and particularly recombinant adeno-associated virus (rAAV) to deliver genes and DNA sequences for gene therapy following manipulation of the therapeutic virus for packaging and transport. The invention delivers therapeutic viral vectors via rAAV affixed to support matrixes (i.e., sutures, surgically implantable materials, grafts, and the like).
Public/Granted literature
- US20080014246A1 METHODS AND COMPOUNDS FOR CONTROLLED RELEASE OF RECOMBINANT PARVOVIRUS VECTORS Public/Granted day:2008-01-17
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