Invention Grant
US07925125B2 Microfluidic detection device having reduced dispersion and method for making same
有权
具有降低的色散的微流体检测装置及其制造方法
- Patent Title: Microfluidic detection device having reduced dispersion and method for making same
- Patent Title (中): 具有降低的色散的微流体检测装置及其制造方法
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Application No.: US12030078Application Date: 2008-02-12
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Publication No.: US07925125B2Publication Date: 2011-04-12
- Inventor: Douglas R. Cyr , Roger L. Farrow , Don W. Arnold
- Applicant: Douglas R. Cyr , Roger L. Farrow , Don W. Arnold
- Applicant Address: SG Singapore
- Assignee: DH Technologies Development Pte. Ltd.
- Current Assignee: DH Technologies Development Pte. Ltd.
- Current Assignee Address: SG Singapore
- Main IPC: G02B6/00
- IPC: G02B6/00

Abstract:
A microfluidic detection device provides reduced dispersion of axial concentration gradients in a flowing sample. The microfluidic detection device includes a cell body and a flow path through the cell body. The flow path has an inlet segment, an outlet segment, and a central segment, which forms a detection cell. The central segment is located between and at an angle with both the inlet segment and the outlet segment. The central segment has a first junction with the inlet segment and a second junction with the outlet segment. The cell body contains two arms that can transmit light to and from the detection cell. At least a portion of a first arm is located in the first junction and at least a portion of a second arm is located in the second junction. The portions of the arms located in the junctions are situated so that fluid entering or exiting the central segment of the flow path flows around the outer surface of one of the portions. By ensuring that the flow velocity is high near the walls both at the beginning and at the end of the conduit, the configuration serves to counteract dispersion caused by the normal parabolic velocity profile of flow through a cylindrical conduit, where the fluid velocity is highest at the center. In addition, the configuration promotes efficient sweeping of the entire volume between the two arms. A method for manufacturing the microfluidic detection device is also provided.
Public/Granted literature
- US20080216951A1 Microfluidic Detection Device Having Reduced Dispersion And Method For Making Same Public/Granted day:2008-09-11
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