Vehicle body structure includes: a sub frame mounted to a vehicle body frame via elastic members and having at least one of suspensions and a power source supported thereon; a collision detecting sensor; and load transmitting connection mechanisms for connecting the sub frame to the vehicle body frame once the collision detecting sensor detects a collision of the vehicle. Load transmission characteristic provided between the vehicle body frame and the sub frame by the load transmitting connection mechanism is greater than a load transmission characteristic provided by the elastic bushes.