Invention Grant
US07927579B2 Tandem analyses of noncovalently driven effectors for modulatory mapping of activities of protein sites
有权
用于非蛋白质驱动效应物的串联分析用于蛋白质位点活性的调节作图
- Patent Title: Tandem analyses of noncovalently driven effectors for modulatory mapping of activities of protein sites
- Patent Title (中): 用于非蛋白质驱动效应物的串联分析用于蛋白质位点活性的调节作图
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Application No.: US10759513Application Date: 2004-01-16
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Publication No.: US07927579B2Publication Date: 2011-04-19
- Inventor: Alexander Krantz
- Applicant: Alexander Krantz
- Applicant Address: US CA San Francisco
- Assignee: Advanced Proteome Therapeutics, Inc
- Current Assignee: Advanced Proteome Therapeutics, Inc
- Current Assignee Address: US CA San Francisco
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Brian C. Trinque
- Main IPC: A61K51/00
- IPC: A61K51/00
Abstract:
The present invention provides methods of discovering and mapping secondary binding sites on biological molecules (e.g., proteins), the effects, if any, of site occupancy on the primary function of the molecule, and the screening of small molecules against the secondary binding sites. The invention further provides novel complexes for modification of secondary binding sites and the resulting modified biological molecules.
Public/Granted literature
- US20040176575A1 Tandem analyses of noncovalently driven effectors for modulatory mapping of activities of protein sites Public/Granted day:2004-09-09
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