Invention Grant
- Patent Title: Sustained release preparations and process for producing the same
- Patent Title (中): 缓释制剂及其制备方法
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Application No.: US10504978Application Date: 2003-02-20
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Publication No.: US07927628B2Publication Date: 2011-04-19
- Inventor: Tomohira Yuso
- Applicant: Tomohira Yuso
- Applicant Address: JP Tokyo
- Assignee: Otsuka Pharmaceutical Co., Ltd.
- Current Assignee: Otsuka Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2002-044460 20020221
- International Application: PCT/JP03/01837 WO 20030220
- International Announcement: WO03/070223 WO 20030828
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K9/16 ; A61K9/50
Abstract:
The present invention provides sustained-release preparations from which a pharmacologically active substance can be released over a long time and a process for producing the same. Such a sustained-release preparation is produced by melt-granulating a low-melting-point substance and a pharmacologically active substance and melt-coating the surface of the thus obtained particles with (1) a fine powder of a water-insoluble polymer or (2) a fine powder of a water-insoluble polymer and at least one member selected from the group consisting of talc, magnesium stearate and titanium oxide.
Public/Granted literature
- US20050106245A1 Sustained release preparations and process for producing the same Public/Granted day:2005-05-19
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