High molar succinate yield bacteria by increasing the intracellular NADH availability

Invention Grant

US07927859B2 High molar succinate yield bacteria by increasing the intracellular NADH availability 有权

Title translation: 高摩尔琥珀酸盐通过增加细胞内NADH的可用性而产生细菌

Patent Title: High molar succinate yield bacteria by increasing the intracellular NADH availability
Patent Title (中): 高摩尔琥珀酸盐通过增加细胞内NADH的可用性而产生细菌
Application No.: US10923635

Application Date: 2004-08-20
Publication No.: US07927859B2

Publication Date: 2011-04-19
Inventor: Ka-Yiu San , George N. Bennett , Ailen Sánchez
Applicant: Ka-Yiu San , George N. Bennett , Ailen Sánchez
Applicant Address: US TX Houston
Assignee: Rice University
Current Assignee: Rice University
Current Assignee Address: US TX Houston
Agency: Boulware & Valoir
Main IPC: C12N1/20
IPC: C12N1/20 ; C12N9/02 ; C12N9/04 ; C12N9/10 ; C12N15/00 ; C12P7/64 ; C12P21/04 ; C12Q1/68 ; C12Q1/00 ; C07H21/04 ; C07H21/02

Abstract:

The invention relates to increasing the yield of succinate in bacteria by increasing the intracellular availability of cofactors such as NADH.

Abstract(Chinese):

本发明涉及通过增加辅因子如NADH的细胞内可用性来提高细菌中琥珀酸的产量。

Public/Granted literature

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IPC分类:

C	化学；冶金
C12	生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程
C12N	微生物或酶；其组合物；繁殖、保藏或维持微生物；变异或遗传工程；培养基（微生物学的试验介质入C12Q1/00）。
C12N1/00	微生物本身，如原生动物；及其组合物（含有由原生动物、细菌或病毒得到的材料的药物的制备入A61K35/66；从藻类材料制备药物的入A61K36/02；从真菌中材料制备药物的入A61K36/06；药用细菌的抗原或抗体组合物的制备，如细菌菌苗入A61K39/00）；繁殖、维持或保藏微生物或其组合物的方法；制备或分离含有一种微生物的组合物的方法；及其培养基
C12N1/20	.细菌；其培养基