Invention Grant
US07928060B2 Amylin family polypeptide-6 (AFP-6) analogs and methods of making and using them
失效
胰岛淀粉样多肽多肽-6（AFP-6）类似物及其制备和使用方法
- Patent Title: Amylin family polypeptide-6 (AFP-6) analogs and methods of making and using them
- Patent Title (中): 胰岛淀粉样多肽多肽-6（AFP-6）类似物及其制备和使用方法
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Application No.: US11664750Application Date: 2005-10-11
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Publication No.: US07928060B2Publication Date: 2011-04-19
- Inventor: Mary Erickson , Ved Srivastava , Sarah McQuaid , Andrew Young , Richard Pittner , Soumitra Ghosh
- Applicant: Mary Erickson , Ved Srivastava , Sarah McQuaid , Andrew Young , Richard Pittner , Soumitra Ghosh
- Applicant Address: US CA San Diego
- Assignee: Amylin Pharmaceuticals, Inc.
- Current Assignee: Amylin Pharmaceuticals, Inc.
- Current Assignee Address: US CA San Diego
- International Application: PCT/US2005/036456 WO 20051011
- International Announcement: WO2006/042242 WO 20060420
- Main IPC: A61K38/22
- IPC: A61K38/22 ; C07K14/575
Abstract:
The present invention relates to Amylin Family Polypeptide-6 (AFP-6) analogs, which include derivatives and fragments, related nucleic acids, expression constructs, host cells, and processes for recombinant production of the AFP-6 analogs. The AFP-6 analogs of the invention include one or more amino acid sequence modifications. In addition, methods and compositions are disclosed to treat and prevent conditions such as metabolic and cardiovascular disorders, e.g., obesity, diabetes, metabolic syndrome, myocardial ischemia, and increased cardiovascular risk.
Public/Granted literature
- US20080207501A1 Amylin Family Polypeptide-6 (Afp-6) Analogs and Methods of Making and Using Them Public/Granted day:2008-08-28
Information query
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