Invention Grant
- Patent Title: Combined use of PRAME inhibitors and HDAC inhibitors
- Patent Title (中): 组合使用PRAME抑制剂和HDAC抑制剂
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Application No.: US10587023Application Date: 2005-01-27
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Publication No.: US07928081B2Publication Date: 2011-04-19
- Inventor: René Bernards , Mirjam Epping , Liming Wang
- Applicant: René Bernards , Mirjam Epping , Liming Wang
- Applicant Address: NL Amsterdam NL Amsterdam NL Amsterdam
- Assignee: Rene Bernards,Mirjam Epping,Liming Wang
- Current Assignee: Rene Bernards,Mirjam Epping,Liming Wang
- Current Assignee Address: NL Amsterdam NL Amsterdam NL Amsterdam
- International Application: PCT/EP2005/000937 WO 20050127
- International Announcement: WO2005/074995 WO 20050818
- Main IPC: A61K48/00
- IPC: A61K48/00
Abstract:
The invention relates to the cancer antigen PRAME (PReferentially expressed Antigen in MElanoma) and its use in a method of treatment of a tumour which comprises administering to a subject in need of treatment an effective amount of an inhibitor of PRAME, in combination with a second agent selected from the group of an inhibitor of HDAC (an HDACi) and a retinoid.
Public/Granted literature
- US20080119424A1 Combined Use of Prame Inhibitors and Hdac Inhibitors Public/Granted day:2008-05-22
Information query
