Invention Grant
US07928104B2 7-phenylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(ADP-ribose) polymerase inhibitors
有权
7-苯基烷基取代的2-喹啉酮和2-喹喔啉酮作为聚（ADP-核糖）聚合酶抑制剂
- Patent Title: 7-phenylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(ADP-ribose) polymerase inhibitors
- Patent Title (中): 7-苯基烷基取代的2-喹啉酮和2-喹喔啉酮作为聚（ADP-核糖）聚合酶抑制剂
-
Application No.: US10595882Application Date: 2004-11-18
-
Publication No.: US07928104B2Publication Date: 2011-04-19
- Inventor: Dominique Jean-Pierre Mabire , Jérôme Emile Georges Guillemont , Jacobus Alphonsus Josephus Van Dun , Maria Victorina Francisca Somers , Walter Boudewijn Leopold Wouters
- Applicant: Dominique Jean-Pierre Mabire , Jérôme Emile Georges Guillemont , Jacobus Alphonsus Josephus Van Dun , Maria Victorina Francisca Somers , Walter Boudewijn Leopold Wouters
- Priority: EP03078650 20031120
- International Application: PCT/EP2004/013162 WO 20041118
- International Announcement: WO2005/054209 WO 20050616
- Main IPC: A61K31/498
- IPC: A61K31/498 ; C07D401/08
Abstract:
The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, R1, R2, R3, R4, R5, R6 and X have defined meanings.
Public/Granted literature
- US20080249099A1 7-Phenylalkyl Substituted 2-Quinolinones and 2-Quinoxalinones as Poly(Adp-Ribose) Polymerase Inhibitors Public/Granted day:2008-10-09
Information query
IPC分类:
