Invention Grant
- Patent Title: Aza-pyridopyrimidinone derivatives
- Patent Title (中): 氮杂 - 吡啶并嘧啶酮衍生物
-
Application No.: US12049460Application Date: 2008-03-17
-
Publication No.: US07928106B2Publication Date: 2011-04-19
- Inventor: Aurelia Conte , Henrietta Dehmlow , Uwe Grether , Nicole A. Kratochwil , Holger Kuehne , Robert Narquizian , Constantinos G. Panousis , Jens-Uwe Peters , Fabienne Ricklin
- Applicant: Aurelia Conte , Henrietta Dehmlow , Uwe Grether , Nicole A. Kratochwil , Holger Kuehne , Robert Narquizian , Constantinos G. Panousis , Jens-Uwe Peters , Fabienne Ricklin
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Dennis P. Tramaloni; Brian C. Remy
- Priority: EP07104801 20070323
- Main IPC: A61K31/50
- IPC: A61K31/50 ; A61K31/501 ; C07D487/00
Abstract:
The invention is concerned with novel aza-pyridopyrimidinone derivatives of formula (I): wherein R1, R2, R3, R4, R5, X1, X2, X3, Y, Z, m and n are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds are HM74A agonists and can be used in treating or preventing diseases which are modulated by HM74A agonists.
Public/Granted literature
- US20080234277A1 NOVEL AZA-PYRIDOPYRIMIDINONE DERIVATIVES Public/Granted day:2008-09-25
Information query
