A transistor gate driving circuit is developed for power saving. It includes a first high-side transistor, a second high-side transistor and a low-side transistor. A voltage clamp device is connected to the gate terminal of the first high-side transistor to limit the maximum output voltage. A detection circuit is coupled to detect a feedback signal of the power converter. The feedback signal is correlated to the output load of the power converter. The detection circuit will generate a disable signal in response to the level of the feedback signal. The disable signal is coupled to disable the second high-side transistor once the level of the feedback signal is lower than a threshold.