Invention Grant
- Patent Title: Humanized anti-amyloid beta antibodies
- Patent Title (中): 人源化抗淀粉样β抗体
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Application No.: US12323682Application Date: 2008-11-26
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Publication No.: US07931899B2Publication Date: 2011-04-26
- Inventor: Lisa Lynn Shafer , Francis Joseph Carr , James Peter Gregson , Dawn Ann Bembridge , Tim Jones
- Applicant: Lisa Lynn Shafer , Francis Joseph Carr , James Peter Gregson , Dawn Ann Bembridge , Tim Jones
- Applicant Address: US MN Minneapolis
- Assignee: Medtronic, Inc
- Current Assignee: Medtronic, Inc
- Current Assignee Address: US MN Minneapolis
- Agency: Campbell Nelson Whipps LLC
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C12P21/08
Abstract:
Humanized anti-Aβ antibodies derived from a murine antibody directed to a N-terminal epitope of Aβ are described. The humanized antibodies have reduced or no human T cell epitopes and bind Aβ with an affinity similar to that of the murine antibody.
Public/Granted literature
- US20090175923A1 HUMANIZED ANTI-AMYLOID BETA ANTIBODIES Public/Granted day:2009-07-09
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