Invention Grant
- Patent Title: Internalizing anti-CD74 antibodies and methods of use
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Application No.: US12794823Application Date: 2010-06-07
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Publication No.: US07931903B2Publication Date: 2011-04-26
- Inventor: Hans J. Hansen , Zhengxing Qu , David M. Goldenberg
- Applicant: Hans J. Hansen , Zhengxing Qu , David M. Goldenberg
- Applicant Address: US NJ Morris Plains
- Assignee: Immunomedics, Inc.
- Current Assignee: Immunomedics, Inc.
- Current Assignee Address: US NJ Morris Plains
- Agent Richard A. Nakashima
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
The present invention provides humanized, chimeric and human anti-CD74 antibodies, CD74 antibody fusion proteins, immunoconjugates, vaccines and bispecific that bind to CD74, the major histocompatibility complex (MHC) class-II invariant chain, Ii, which is useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies, other malignancies in which the cells are reactive with CD74, and autoimmune diseases, and methods of treatment and diagnosis.
Public/Granted literature
- US20100266497A1 Internalizing Anti-CD74 Antibodies and Methods of Use Public/Granted day:2010-10-21
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