Invention Grant
- Patent Title: Method for preparing modified collagen outside a host cell
- Patent Title (中): 在宿主细胞外制备改性胶原蛋白的方法
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Application No.: US11547822Application Date: 2005-04-07
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Publication No.: US07932053B2Publication Date: 2011-04-26
- Inventor: Rudolf Antonius Bank , Anne-Marie Zuurmond , Johannes Petrus M. Jore , Cornelius Antonius M. J. J. van den Hondel
- Applicant: Rudolf Antonius Bank , Anne-Marie Zuurmond , Johannes Petrus M. Jore , Cornelius Antonius M. J. J. van den Hondel
- Applicant Address: NL Delft
- Assignee: Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek TNO
- Current Assignee: Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek TNO
- Current Assignee Address: NL Delft
- Agency: Morrison & Foerster LLP
- Priority: EP04076096 20040408
- International Application: PCT/NL2005/000264 WO 20050407
- International Announcement: WO2005/097829 WO 20051020
- Main IPC: C12P21/00
- IPC: C12P21/00
Abstract:
The present invention relates to a method for preparing a modified folded protein, comprising modifying unfolded a-chains comprising a collagenous amino acid sequence and thereafter folding at least part of the modified a-chains into a quaternary protein structure, in particular a helical protein structure. The invention allows for an attractive alternative for making recombinant proteins, such as recombinant collagens and the like, which may be used in a variety of biomedical and other applications.
Public/Granted literature
- US20080086782A1 Method for Preparing Modified Collagen Outside a Host Cell Public/Granted day:2008-04-10
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