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US07932064B2 Processes for making (R)-ethyl 4-cyano-3-hydroxybutyric acid 有权
制备(R)-4-氰基-3-羟基丁酸的方法

Processes for making (R)-ethyl 4-cyano-3-hydroxybutyric acid
Abstract:
The invention provides novel processes for making ethyl-4-cyano-3-hydroxybutyrate, e.g., (R)-ethyl 4-cyano-3-hydroxybutyric acid, and 4-cyano-3-hydroxybutyric acid. The invention provides protocols for making and 4-cyano-3-hydroxybutyric acid and ethyl-4-cyano-3-hydroxybutyrate by whole cell processes, cell lysate processes, “one pot processes” and “multi-pot” processes using a variety of parameters.
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