Invention Grant
- Patent Title: Modified leukotoxin gene and protein
- Patent Title (中): 改良白细胞毒素基因和蛋白质
-
Application No.: US12833512Application Date: 2010-07-09
-
Publication No.: US07932085B2Publication Date: 2011-04-26
- Inventor: Reggie Y. C. Lo , Patricia E. Shewen , Raymond W. H. Lee , Doug Hodgins , Judith N. Strommer
- Applicant: Reggie Y. C. Lo , Patricia E. Shewen , Raymond W. H. Lee , Doug Hodgins , Judith N. Strommer
- Applicant Address: CA Guelph, Ontario
- Assignee: University of Guelph
- Current Assignee: University of Guelph
- Current Assignee Address: CA Guelph, Ontario
- Agency: Bereskin & Parr LLP
- Agent Micheline Gravelle
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C12N5/10 ; A01H5/00 ; A61P31/04
Abstract:
The present invention provides nucleic acid sequences encoding a modified leukotoxin protein, wherein the modification comprises the removal of nucleic acid sequences encoding amino acids within hydrophobic transmembrane domains of full length leukotoxin protein, preferably from Mannheimia haemolytica. The modified leukotoxin proteins are useful in vaccine compositions effective against Mannheimia haemolytica in animals.
Public/Granted literature
- US20110002951A1 Modified Leukotoxin Gene and Protein Public/Granted day:2011-01-06
Information query
