Invention Grant
- Patent Title: Small molecule printing
- Patent Title (中): 小分子印刷
-
Application No.: US10370885Application Date: 2003-02-20
-
Publication No.: US07932213B2Publication Date: 2011-04-26
- Inventor: Seung Bum Park , David Barnes-Seeman , Angela N. Koehler , Stuart L. Schreiber
- Applicant: Seung Bum Park , David Barnes-Seeman , Angela N. Koehler , Stuart L. Schreiber
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Agent C. Hunter Baker
- Main IPC: C40B40/04
- IPC: C40B40/04 ; C40B30/04 ; C40B50/08 ; C40B60/04 ; G01N33/566 ; G01N33/543 ; G01N33/53
Abstract:
The present invention provides compositions and methods to facilitate the identification of compounds that are capable of interacting with a biological macromolecule of interest. A composition is provided that comprises an array of chemical compounds attached to a solid support, wherein the density of the array of compounds is at least 1000 spots per cm2. The inventive arrays are generated by: providing a solid support functionalized with a selected chemical moiety capable of interacting with a chemical compound to form an attachment and delivering compounds to the solid support having a density of at least 1000 spots per cm2. The present invention also provides methods for utilizing these arrays to identify small molecule partners for biological macromolecules of interest.
Public/Granted literature
- US20030215876A1 Small molecule printing Public/Granted day:2003-11-20
Information query
