Invention Grant
US07932244B2 Bile acid derivatives as FXR ligands for the prevention or treatment of FXR-mediated diseases or conditions
有权
胆酸衍生物作为FXR配体，用于预防或治疗FXR介导的疾病或病症
- Patent Title: Bile acid derivatives as FXR ligands for the prevention or treatment of FXR-mediated diseases or conditions
- Patent Title (中): 胆酸衍生物作为FXR配体，用于预防或治疗FXR介导的疾病或病症
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Application No.: US11819517Application Date: 2007-06-27
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Publication No.: US07932244B2Publication Date: 2011-04-26
- Inventor: Roberto Pellicciari , Stefano Fiorucci , Mark Pruzanski
- Applicant: Roberto Pellicciari , Stefano Fiorucci , Mark Pruzanski
- Applicant Address: US NY New York
- Assignee: Intercept Pharmaceuticals, Inc.
- Current Assignee: Intercept Pharmaceuticals, Inc.
- Current Assignee Address: US NY New York
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky, and Popeo, P.C.
- Agent Ivor R. Elrifi, Esq.; Jennifer L. Loebach, Esq.
- Main IPC: A61K31/575
- IPC: A61K31/575 ; C07C9/00
Abstract:
The present invention relates to compounds of formula (I): wherein R is hydrogen or alpha-hydroxy, the hydroxyl group in position 7 is in the alpha or beta position; and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof.
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