Invention Grant
- Patent Title: Sinomenine derivatives and preparation and uses thereof
- Patent Title (中): 青藤碱衍生物及其制备及用途
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Application No.: US12096543Application Date: 2006-12-15
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Publication No.: US07932264B2Publication Date: 2011-04-26
- Inventor: Jie Wang , Yi Pan
- Applicant: Jie Wang , Yi Pan
- Applicant Address: US NJ Englewood Cliffs
- Assignee: Naturemed Group Corporation
- Current Assignee: Naturemed Group Corporation
- Current Assignee Address: US NJ Englewood Cliffs
- Agency: Law Offices of Albert Wai-Kit Chan, PLLC
- Priority: CN200510123089 20051215; CN200510123090 20051215; CN200610038862 20060315
- International Application: PCT/US2006/048086 WO 20061215
- International Announcement: WO2007/070703 WO 20070621
- Main IPC: C07D221/28
- IPC: C07D221/28 ; A61K31/485
Abstract:
The present invention relates to the preparation and pharmacological use of sinomenine derivatives of formula I. The approach disclosed herein is the modification of D ring by-substituting for R. Additional substitutions in the other rings are also provided herein. Several of the sinomenine derivatives have significantly greater anti-inflammation activity when compared with the parent compound.
Public/Granted literature
- US20080318966A1 Sinomenine Derivatives and Preparation and Uses Thereof Public/Granted day:2008-12-25
Information query
