Invention Grant
US07932275B2 2-aminopyridine compounds useful as β-secretase inhibitors for the treatment of alzheimer's disease
有权
用作治疗阿尔茨海默病的分泌酶抑制剂的2-氨基吡啶化合物
- Patent Title: 2-aminopyridine compounds useful as β-secretase inhibitors for the treatment of alzheimer's disease
- Patent Title (中): 用作治疗阿尔茨海默病的分泌酶抑制剂的2-氨基吡啶化合物
-
Application No.: US11666942Application Date: 2005-10-25
-
Publication No.: US07932275B2Publication Date: 2011-04-26
- Inventor: Craig A. Coburn , M. Katharine Holloway , Shawn J. Stachel
- Applicant: Craig A. Coburn , M. Katharine Holloway , Shawn J. Stachel
- Applicant Address: US NJ Rahway
- Assignee: Merck, Sharp & Dohme Corp.
- Current Assignee: Merck, Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Keith D. MacMillan; Gerard M. Devlin
- International Application: PCT/US2005/039932 WO 20051025
- International Announcement: WO2006/060109 WO 20060608
- Main IPC: C07D213/73
- IPC: C07D213/73
Abstract:
The present invention is directed to 2-aminopyridine compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
Public/Granted literature
- US20080161363A1 2-Aminopyridine Compounds Useful as Beta-Secretase Inhibitors For the Treatment of Alzheimer's Disease Public/Granted day:2008-07-03
Information query
IPC分类:
