Invention Grant
US07932355B2 Virally-safe factor VIII with a low content of higher multimers
有权
具有低含量较高多聚体的病毒安全因子VIII
- Patent Title: Virally-safe factor VIII with a low content of higher multimers
- Patent Title (中): 具有低含量较高多聚体的病毒安全因子VIII
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Application No.: US10576794Application Date: 2004-10-25
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Publication No.: US07932355B2Publication Date: 2011-04-26
- Inventor: Abdessatar Chtourou , Michel Nogre , Roland Schmitthaeusler
- Applicant: Abdessatar Chtourou , Michel Nogre , Roland Schmitthaeusler
- Applicant Address: FR Les Ulis
- Assignee: LFB SA
- Current Assignee: LFB SA
- Current Assignee Address: FR Les Ulis
- Agency: Foley & Lardner LLP
- Priority: FR0312398 20031023
- International Application: PCT/FR2004/002737 WO 20041025
- International Announcement: WO2005/040214 WO 20050506
- Main IPC: A61K35/14
- IPC: A61K35/14 ; A23J1/00 ; C12N7/04
Abstract:
La present invention pertains to a composition of plasma-derived virally-safe factor VIII, obtained after nanometric filtration, said composition comprising von Willebrand factor (vWF) at a rate of 15% or less of decamers and higher multimers. Such compositions have a reduction factor of the virus titre higher than 4 log and are thus suitable for treatment of hemophilia.
Public/Granted literature
- US20070275880A1 Virally-Safe Factor VIII with a Low Content of Higher Multimers Public/Granted day:2007-11-29
Information query
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