Invention Grant
- Patent Title: Process for preparing pyrrole derivatives and intermediates
- Patent Title (中): 制备吡咯衍生物和中间体的方法
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Application No.: US11722318Application Date: 2005-12-16
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Publication No.: US07932403B2Publication Date: 2011-04-26
- Inventor: Pavel Bobal , Jaroslav Frantisek , Jiri Stohandl , Kane Denike , Armin Boerner , Vitali Tararov , Andrei Korostylev , Gerd Koenig , Nicolas Jeker
- Applicant: Pavel Bobal , Jaroslav Frantisek , Jiri Stohandl , Kane Denike , Armin Boerner , Vitali Tararov , Andrei Korostylev , Gerd Koenig , Nicolas Jeker
- Applicant Address: DE Ulm
- Assignee: ratiopharm GmbH
- Current Assignee: ratiopharm GmbH
- Current Assignee Address: DE Ulm
- Agency: Smith Patent Consulting, LLC
- Agent Chalin Smith
- Priority: EP04030159 20041220
- International Application: PCT/EP2005/013588 WO 20051216
- International Announcement: WO2006/066823 WO 20060629
- Main IPC: C07D207/33
- IPC: C07D207/33 ; C07D207/335
Abstract:
The present invention relates to a process for preparing pyrrole derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, and more particularly to improved synthetic methods for preparing 3,5-dihydroxy-7-pyrrol-1-yl heptanoic acids from 1,4-diketo starting materials. The invention further relates to intermediates in this process formula (I).
Public/Granted literature
- US20090012312A1 Process for Preparing Pyrrole Derivatives and Intermediates Public/Granted day:2009-01-08
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