An industrial control system includes a machine, a machine controller, and a safety controller. The machine controller is operable to identify a need for a human interaction, place the machine into a ready state for the human interaction, and generate a ready message responsive to placing the machine into the ready state. The safety controller is operable to receive the ready message, place the machine into a safe state responsive to receiving the ready message, and provide a human interaction indication responsive to placing the machine into the safe state.