Invention Grant
- Patent Title: Apparatus and method for analysis of dry powder inhaler products
- Patent Title (中): 干粉吸入器产品分析装置及方法
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Application No.: US11948249Application Date: 2007-11-30
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Publication No.: US07934434B2Publication Date: 2011-05-03
- Inventor: Christopher M. Shelton , Timothy J. Stephens
- Applicant: Christopher M. Shelton , Timothy J. Stephens
- Applicant Address: US MD Rockville
- Assignee: Pharmaceutical Product Development, Inc.
- Current Assignee: Pharmaceutical Product Development, Inc.
- Current Assignee Address: US MD Rockville
- Agency: Sheridan Ross, P.C.
- Main IPC: G01N1/24
- IPC: G01N1/24 ; G01N1/14 ; G01N1/40

Abstract:
An apparatus and method are provided for collection and analysis of dry powder inhaler products to determine foreign particulate matter found therein. The apparatus includes a collection chamber that communicates directly with the mouthpiece of a dry powder inhaler device. The collection chamber is used to both collect product samples, as well as to mix the samples with a diluent that places the active pharmaceutical components and excipients in solution, while the foreign particulate matter remains suspended. Analysis of a sample is preferably conducted by light obscuration wherein a probe is inserted directly within the collection chamber of the apparatus. An integral magnetic stir-bar incorporated within the apparatus eliminates the need to transfer the collected sample to a secondary vessel for mixing or analysis.
Public/Granted literature
- US20090139352A1 APPARATUS AND METHOD FOR ANALYSIS OF DRY POWDER INHALER PRODUCTS Public/Granted day:2009-06-04
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