Invention Grant
US07935347B2 DNA sequence, and recombinant preparation of group 4 major allergens from cereals
有权
DNA序列和来自谷物的第4组主要变应原的重组制备
- Patent Title: DNA sequence, and recombinant preparation of group 4 major allergens from cereals
- Patent Title (中): DNA序列和来自谷物的第4组主要变应原的重组制备
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Application No.: US10583089Application Date: 2004-12-01
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Publication No.: US07935347B2Publication Date: 2011-05-03
- Inventor: Andreas Nandy , Helmut Fiebig , Oliver Cromwell
- Applicant: Andreas Nandy , Helmut Fiebig , Oliver Cromwell
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano, Branigan, P.C.
- Priority: DE10359351 20031216
- International Application: PCT/EP2004/013664 WO 20041201
- International Announcement: WO2005/059136 WO 20050630
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K39/00 ; A61K39/35 ; A61K39/36 ; A01N37/18 ; C07K1/00 ; C07K14/00 ; C07K17/00
Abstract:
The invention relates to the preparation of DNA sequences of group 4 major allergens from cereals. The invention also includes fragments, novel combinations of partial sequences and point mutations with hypoallergenic effects. The recombinant DNA molecules and the derived polypeptides, fragments, novel combinations of partial sequences and variants can be used for therapy of pollen-allergy diseases. The proteins produced by recombination can be applied to in-vitro and in-vivo diagnosis of pollen allergies.
Public/Granted literature
- US20080108561A1 Dna Sequence, and Recombinant Preparation of Group 4 Major Allergens From Cereals Public/Granted day:2008-05-08
Information query
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