Invention Grant
- Patent Title: Hepatocyte growth factor (HGF) binding proteins
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Application No.: US12632758Application Date: 2009-12-07
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Publication No.: US07935502B2Publication Date: 2011-05-03
- Inventor: May Han , S. Kirk Wright , William M. Winston, Jr. , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris
- Applicant: May Han , S. Kirk Wright , William M. Winston, Jr. , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris
- Applicant Address: US MA Cambridge
- Assignee: AVEO Pharmaceuticals, Inc.
- Current Assignee: AVEO Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Goodwin Procter LLP
- Main IPC: C12P21/06
- IPC: C12P21/06 ; C12N5/07 ; C12N15/63 ; C07H21/04
Abstract:
The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
Public/Granted literature
- US20100173361A1 Hepatocyte Growth Factor (HGF) Binding Proteins Public/Granted day:2010-07-08
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