Invention Grant
- Patent Title: Mutant receptors and their use in a nuclear receptor-based inducible gene expression system
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Application No.: US11118855Application Date: 2005-04-29
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Publication No.: US07935510B2Publication Date: 2011-05-03
- Inventor: Subba Reddy Palli , Mohan Basavaraju Kumar
- Applicant: Subba Reddy Palli , Mohan Basavaraju Kumar
- Applicant Address: US VA Blacksburg
- Assignee: Intrexon Corporation
- Current Assignee: Intrexon Corporation
- Current Assignee Address: US VA Blacksburg
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C12N5/00 ; C12N1/00 ; C12N15/00 ; C12P21/04 ; C12P21/06 ; C07H21/04 ; C07H21/02

Abstract:
This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system and methods of modulating the expression of a gene in a host cell for applications such as gene therapy, large scale production of proteins and antibodies, cell-based high throughput screening assays, functional genomics and regulation of traits in transgenic organisms.
Public/Granted literature
- US20050266457A1 Mutant receptors and their use in a nuclear receptor-based inducible gene expression system Public/Granted day:2005-12-01
Information query
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