Invention Grant
- Patent Title: Methods for the early diagnosis of ovarian cancer
- Patent Title (中): 卵巢癌早期诊断方法
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Application No.: US10135795Application Date: 2002-04-30
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Publication No.: US07935531B2Publication Date: 2011-05-03
- Inventor: Timothy J. O'Brien , Martin J. Cannon , Alessandro Santin
- Applicant: Timothy J. O'Brien , Martin J. Cannon , Alessandro Santin
- Applicant Address: US AR Little Rock
- Assignee: Board of Trustees of the University of Arkansas
- Current Assignee: Board of Trustees of the University of Arkansas
- Current Assignee Address: US AR Little Rock
- Agent Benjamin Aaron Adler
- Main IPC: C12N15/00
- IPC: C12N15/00 ; A01N63/00
Abstract:
The disclosed nucleic acid primer sets, used in combination with quantitative amplification (PCR) of tissue cDNA, can indicate the presence of specific proteases in a tissue sample. Specifically, the present invention relates to expression of hepsin protease. The detected proteases are themselves specifically over-expressed in certain cancers, and the presence of their genetic precursors may serve for early detection of associated ovarian and other malignancies, and for the design of interactive therapies for cancer treatment.
Public/Granted literature
- US20030077618A1 Methods for the early diagnosis of ovarian cancer Public/Granted day:2003-04-24
Information query
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