Invention Grant
US07935676B2 Nucleic acid construct containing a nucleic acid derived from the genome of hepatitis C virus (HCV) of genotype 2A, and a cell having such nucleic acid construct introduced therein
有权
含有源自基因型2A的丙型肝炎病毒（HCV）的基因组的核酸的核酸构建体以及引入其中的这种核酸构建体的细胞
- Patent Title: Nucleic acid construct containing a nucleic acid derived from the genome of hepatitis C virus (HCV) of genotype 2A, and a cell having such nucleic acid construct introduced therein
- Patent Title (中): 含有源自基因型2A的丙型肝炎病毒（HCV）的基因组的核酸的核酸构建体以及引入其中的这种核酸构建体的细胞
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Application No.: US10558155Application Date: 2003-11-25
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Publication No.: US07935676B2Publication Date: 2011-05-03
- Inventor: Takaji Wakita , Takanobu Kato , Tomoko Date
- Applicant: Takaji Wakita , Takanobu Kato , Tomoko Date
- Applicant Address: JP Tokyo JP Tokyo DE Schriesheim
- Assignee: Toray Industries Inc.,Tokyo Metropolitan Organization for Medical Research,Ralf Bartenschlager
- Current Assignee: Toray Industries Inc.,Tokyo Metropolitan Organization for Medical Research,Ralf Bartenschlager
- Current Assignee Address: JP Tokyo JP Tokyo DE Schriesheim
- Agency: Birch, Stewart, Kolasch and Birch, LLP
- Priority: JP2003-148242 20030526; JP2003-329115 20030919
- International Application: PCT/JP03/15038 WO 20031125
- International Announcement: WO2004/104198 WO 20041202
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/11
Abstract:
The present invention relates to a replicon RNA comprising a nucleotide sequence at least containing the 5′ untranslated region, the nucleotide sequence encoding NS3 protein, NS4A protein, NS4B protein, NS5A protein and NS5B protein, and the 3′ untranslated region on the genomic RNA of hepatitis C virus of genotype 2a.
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