Invention Grant
US07935693B2 Polycyclic aryl substituted triazoles and polycyclic heteroaryl substituted triazoles useful as Axl inhibitors
有权
可用作Axl抑制剂的多环芳基取代的三唑和多环杂芳基取代的三唑
- Patent Title: Polycyclic aryl substituted triazoles and polycyclic heteroaryl substituted triazoles useful as Axl inhibitors
- Patent Title (中): 可用作Axl抑制剂的多环芳基取代的三唑和多环杂芳基取代的三唑
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Application No.: US11967163Application Date: 2007-12-29
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Publication No.: US07935693B2Publication Date: 2011-05-03
- Inventor: Rajinder Singh , Dane Goff , Jiaxin Yu , Sacha Holland , Jing Zhang , Thilo J. Heckrodt , Pingyu Ding , Joane Litvak
- Applicant: Rajinder Singh , Dane Goff , Jiaxin Yu , Sacha Holland , Jing Zhang , Thilo J. Heckrodt , Pingyu Ding , Joane Litvak
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Seed IP Law Group PLLC
- Main IPC: A61K31/4196
- IPC: A61K31/4196 ; A61K31/496 ; A61K31/55 ; A61P35/00 ; A61P35/02 ; A61K31/397 ; C07D249/14 ; C07D239/70 ; C07D403/14

Abstract:
Polycyclic aryl and polycyclic heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl. Methods of using the compounds in treating diseases or conditions associated with Axl catalytic activity are also disclosed.
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