Invention Grant
- Patent Title: Piperazines and piperidines as Mglur5 potentiators
- Patent Title (中): 哌嗪和哌啶类作为Mglur5增效剂
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Application No.: US12160959Application Date: 2007-01-05
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Publication No.: US07935703B2Publication Date: 2011-05-03
- Inventor: Abdelmalik Slassi , Methvin Isaac , Jalaj Arora , Dean Brown
- Applicant: Abdelmalik Slassi , Methvin Isaac , Jalaj Arora , Dean Brown
- Applicant Address: SE Sodertalje
- Assignee: AstraZeneca AB
- Current Assignee: AstraZeneca AB
- Current Assignee Address: SE Sodertalje
- Agency: Connolly Bove Lodge & Hutz, LLP
- International Application: PCT/US2007/000231 WO 20070105
- International Announcement: WO2007/087135 WO 20070802
- Main IPC: A61K31/497
- IPC: A61K31/497 ; A61K31/4965 ; A61K31/445 ; A01N43/40 ; C07D211/60 ; C07D403/00 ; C07D241/04 ; C07D295/00 ; C07D401/00

Abstract:
Compounds of Formula I or pharmaceutically acceptable salts or solvates thereof: wherein Ar1, Ar2, A, X, Y, m, n and R1, R2, R3, R4 and R5 are as described in the specification, processes for their preparation, pharmaceutical formulations comprising them and their use in therapy, particularly in the therapy of neurological and psychiatric disorders associated with glutamate dysfunction.
Public/Granted literature
- US20090023711A1 Piperazines and Piperidines as Mglur5 Potentiators Public/Granted day:2009-01-22
Information query
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