Invention Grant
- Patent Title: Formulations which stabilize and inhibit precipitation of immunogenic compositions
- Patent Title (中): 稳定和抑制免疫原性组合物沉淀的制剂
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Application No.: US11737674Application Date: 2007-04-19
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Publication No.: US07935787B2Publication Date: 2011-05-03
- Inventor: Lakshmi Khandke , Ronald Malone , Xudong Yang , Hanyoung Han , Jee Loon Look , Zhaowei Jin , Robert C. Seid, Jr. , Ying Chen
- Applicant: Lakshmi Khandke , Ronald Malone , Xudong Yang , Hanyoung Han , Jee Loon Look , Zhaowei Jin , Robert C. Seid, Jr. , Ying Chen
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Main IPC: A61K31/715
- IPC: A61K31/715 ; C07K14/00

Abstract:
The present invention addresses an ongoing need in the art to improve the stability of immunogenic compositions such as polysaccharide-protein conjugates and protein immunogens. The invention broadly relates to novel formulations which stabilize and inhibit precipitation of immunogenic compositions. More particularly, the invention described hereinafter, addresses a need in the art for formulations which stabilize and inhibit particulate formation (e.g., aggregation, precipitation) of immunogenic compositions which are processed, developed, formulated, manufactured and/or stored in container means such as fermentors, bioreactors, vials, flasks, bags, syringes, rubber stoppers, tubing and the like.
Public/Granted literature
- US20070253984A1 NOVEL FORMULATIONS WHICH STABILIZE AND INHIBIT PRECIPITATION OF IMMUNOGENIC COMPOSITIONS Public/Granted day:2007-11-01
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