Invention Grant
- Patent Title: RNA detection assays
- Patent Title (中): RNA检测分析
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Application No.: US11642815Application Date: 2006-12-19
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Publication No.: US07935800B2Publication Date: 2011-05-03
- Inventor: Hatim T. Allawi , Brad T. Argue , Christian Tor Bartholomay , LuAnne Chehak , Michelle L. Curtis , Peggy S. Eis , Jeff G. Hall , Hon S. Ip , Lin Ji , Michael W. Kaiser , Robert W. Kwiatkowski , Andrew A. Lukowiak , Victor Lyamichev , Natalie E. Lyamicheva , WuPo Ma , Bruce P. Neri , Sarah M. Olson , Marilyn C. Olson-Munoz , James J. Schaefer , Zbigniev Skrzypczynski , Tsetska Y Takova , Lisa C. Thompson , Kevin L. Vedvik
- Applicant: Hatim T. Allawi , Brad T. Argue , Christian Tor Bartholomay , LuAnne Chehak , Michelle L. Curtis , Peggy S. Eis , Jeff G. Hall , Hon S. Ip , Lin Ji , Michael W. Kaiser , Robert W. Kwiatkowski , Andrew A. Lukowiak , Victor Lyamichev , Natalie E. Lyamicheva , WuPo Ma , Bruce P. Neri , Sarah M. Olson , Marilyn C. Olson-Munoz , James J. Schaefer , Zbigniev Skrzypczynski , Tsetska Y Takova , Lisa C. Thompson , Kevin L. Vedvik
- Applicant Address: US WI Madison
- Assignee: Third Wave Technologies, Inc.
- Current Assignee: Third Wave Technologies, Inc.
- Current Assignee Address: US WI Madison
- Agency: Casimir Jones, S.C.
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C12Q1/68 ; C07K1/00
Abstract:
The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. In some embodiments, the 5′ nuclease activity of a variety of enzymes is used to cleave a target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.
Public/Granted literature
- US20080293046A1 RNA detection assays Public/Granted day:2008-11-27
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