Invention Grant
US07935806B2 Method for performing in vitro diagnosis using gene regulation mechanisms and corresponding diagnosis kit
有权
使用基因调控机制进行体外诊断的方法和相应的诊断试剂盒
- Patent Title: Method for performing in vitro diagnosis using gene regulation mechanisms and corresponding diagnosis kit
- Patent Title (中): 使用基因调控机制进行体外诊断的方法和相应的诊断试剂盒
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Application No.: US10496747Application Date: 2002-12-04
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Publication No.: US07935806B2Publication Date: 2011-05-03
- Inventor: Benoit Granier , Sophie Lepage
- Applicant: Benoit Granier , Sophie Lepage
- Applicant Address: BE Liege (Angleur)
- Assignee: Unisensor S.A.
- Current Assignee: Unisensor S.A.
- Current Assignee Address: BE Liege (Angleur)
- Agency: Merchant & Gould P.C.
- Priority: EP01870273 20011206
- International Application: PCT/BE02/00183 WO 20021204
- International Announcement: WO03/048770 WO 20030612
- Main IPC: C07H21/04
- IPC: C07H21/04

Abstract:
The invention concerns a kit for detecting and/or quantifying a ligant (C), present in an analysis sample, by a receptor (A), characterized in that it comprises the following reagents: a single-stranded or double-stranded nucleotide sequence (B), and said receptor (A) consisting of a monomeric or multimeric proteinic entity including at least a first recognition site specific for said ligand (C) and a second recognition site specific for said nucleotide sequence (B); said ligand (C) being capable of positively or negatively modulating fixing of the receptor (A) by its specific recognition site on the nucleotide sequence (B).
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