Invention Grant
- Patent Title: siRNA target hypoxia-inducible factor 1
- Patent Title (中): siRNA靶向缺氧诱导因子1
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Application No.: US12798802Application Date: 2010-04-12
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Publication No.: US07935813B2Publication Date: 2011-05-03
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Kalow & Springut, LLP
- Agent Scott D. Locke, Esq.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07H21/02 ; A61K48/00
Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed.
Public/Granted literature
- US20100234583A1 siRNA target hypoxia-inducible factor 1 Public/Granted day:2010-09-16
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