Invention Grant
US07935814B2 Nitroguanosine-3′ 5′-cyclic monophosphate compound and protein kinase G activating agent 有权
硝基鸟苷-3'5'-环状单磷酸化合物和蛋白激酶G活化剂

  • Patent Title: Nitroguanosine-3′ 5′-cyclic monophosphate compound and protein kinase G activating agent
  • Patent Title (中): 硝基鸟苷-3'5'-环状单磷酸化合物和蛋白激酶G活化剂
  • Application No.: US11817168
    Application Date: 2006-02-28
  • Publication No.: US07935814B2
    Publication Date: 2011-05-03
  • Inventor: Takaaki AkaikeTeruo Akuta
  • Applicant: Takaaki AkaikeTeruo Akuta
  • Applicant Address: JP Kumamoto
  • Assignee: Kumamoto University
  • Current Assignee: Kumamoto University
  • Current Assignee Address: JP Kumamoto
  • Agency: Greenblum & Bernstein, PLC
  • Priority: JP2005-052649 20050228
  • International Application: PCT/JP2006/303671 WO 20060228
  • International Announcement: WO2006/093110 WO 20060908
  • Main IPC: C07H19/213
  • IPC: C07H19/213
Nitroguanosine-3′ 5′-cyclic monophosphate compound and protein kinase G activating agent
Abstract:
An object of the present invention is to provide a novel compound that is an agonist of guanosine-3′,5′-cyclic monophosphate and has an effect of activating protein kinase G. The present invention provides 8-guanosine-3′,5′-cyclic monophosphate compound which is represented by the following formula, and a pharmaceutical composition, especially a protein kinase G activating agent, which contains the 8-guanosine-3′,5′-cyclic monophosphate compound as an active ingredient.
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