Invention Grant
US07935816B2 Molecular transporter compositions comprising dendrimeric oligoguanidine with a triazine core that facilitate delivery into cells in vivo
有权
分子转运蛋白组合物，其包含具有三嗪核心的树状聚寡聚核苷酸，其有助于体内递送到细胞中
- Patent Title: Molecular transporter compositions comprising dendrimeric oligoguanidine with a triazine core that facilitate delivery into cells in vivo
- Patent Title (中): 分子转运蛋白组合物，其包含具有三嗪核心的树状聚寡聚核苷酸，其有助于体内递送到细胞中
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Application No.: US11977800Application Date: 2007-10-25
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Publication No.: US07935816B2Publication Date: 2011-05-03
- Inventor: Yong-Fu Li
- Applicant: Yong-Fu Li
- Applicant Address: US OR Philomath
- Assignee: Gene Tools, LLC
- Current Assignee: Gene Tools, LLC
- Current Assignee Address: US OR Philomath
- Agency: Teri G. Andrews Attorney at Law
- Main IPC: A61K47/48
- IPC: A61K47/48 ; C07D403/04 ; C07H21/00
Abstract:
Preparations of novel molecular transporter compositions and their use for transporting bioactive substances into cells in living animals are disclosed. To afford in vivo delivery, the composition is covalently linked to the bioactive substance and the resultant composite structure is introduced into the subject. The transporter composition includes multiple guanidine moieties on a dendrimeric scaffold having a triazine core.
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